ABSTRACT
Objective To study the correlation of supratentorial gliomas and ependymoma between the features of pathology and the characteristic of CT,MRI and provide relevant data for diagnosis and treatment.Methods We analysised 60 patients with gliomas and 40 with ependymoma,contrasted their characteristic of CT,MRI with the features of pathology.Results The feature of irregular appearance,lobulation,tumor wall,tumor tubercle,necrotic cystiform zone,hemorrhage and tumor blood vessels were showed in CT and MRI,which was accord with the alteration of ultrastructure and the expression of tumous label.Conclusion Studying the morphology of supratentorial gliomas and ependymoma may be helpful to raise the veracity of pathologic grading,provide evidence to select treatment,operation and anti-vasoformation of the tumor etc.
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Objective To investigate the correlation of rCBV with vascular endothelial growth factor (VEGF) protein expression and microvessel density (MVD) in gliomas Methods MR examinations were performed preoperatively in 46 patients with suspected supratentorial gliomas All the 46 cases were proved by operation and pathology Immunohistochemical stain methods were used to demonstrate the situation of VEGF protein expression and quantitatively measure the MVD in gliomas The procedures of MR examinations included plain MR scan, PWI and routine contrast enhanced MR scan The pulse sequence of PWI was single shot GRE EPI T 2WI The CBV maps were calculated from the original data of perfusion images and the maximum rCBV of gliomas was acquired from CBV maps through measurement on the region of interest (ROI) According to the situation of VEGF protein expression, all the 46 cases were divided into two groupsincluding positive VEGF protein expression group and negative VEGF protein expression group Mann Whitney U test was used for comparing the difference between the two groups Spearman′s rho correlation analysis was used for observing the correlation between maximum rCBV and MVD in gliomas Results Of the 46 cases; 12 cases were astrocytomas, 3 were oligodendrogliomas, 1 was mixed glioma, 14 were anaplastic astrocytomas, and 16 were glioblastomas multiforme The maximum rCBV value in VEGF(-) group ( n =14) and VEGF(+) group ( n =32) ranged from 0 33～6 63 and 1 03～10 68, with median of 3 08 and 5 95, respectively The difference in maximum rCBV between the two groups was statistically significant ( Mann Whitney U test | z| =2 638, P
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To improve the CT diagnosis of cerebral angioreticuloma, 3 cases of pathologically proven cerebral angioreticuloma were reviewed. The results showed that the image of CT of the first case revealed an irregular, parenchymatous mass located in the right temporallobe and middle cranial fossa.In the second patient,the image showed a annular mass with cystic consistency,surrounded by an area of edema, situated in the right frontal lobe,while in the third patient there was an irregular high density mass with an area of edema lying in the left frontal lobe and along the middle line. Pathological diagnosis of the first patient was mixed angioreticuloma and glioblastoma, and that of the others were angioreticulomas. the results suggested that if the mass in the cerebrum was obviously enhanced in CT, the diagnosis of angioreticuloma should be considered.
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To promote understanding and improve diagnostic level of Rathke′s cysts with CT and MRI,crosscheck analysis was performed between CT,MRI and operative pathology was done in 6 cases.Results: It was misdiagnosed as cranio pharyngioma,hypophysoma and cholesteatoma in CT and MRI before operation.Oval and irregular cystic low density was showed in CT in 4,oval iso density and higher density in 1,respectively,and line like reinforcement of the cystal wall in 2 after intensification.Oval and oval like low signals were showed in 3 and isosignals in 1 on T 1 weighted images of MRI and high signals with clear edge on T 2 weighted images.It suggested that the diagnostic value of MRI was superior to that of CT in Rathke′s cysts.
ABSTRACT
To improve the diagnostic level of CT and MRI in intracranial angioreticuloma. 75 cases of intracranial angioreticuloma were examined by CT, and 19 of them were re examined with MRI. The tumor was located in the cerebellum in 67, frontal lobe in 2, temporal lobe in 1, cerebellum with involvement of medulla, great occipital foramen, vertebral canal, spinal cord and cerebropontial angle in 1, respectively. CT displayed cystic low density accompanied by tumor wall nodules (midcystic tumor) in 35, cystic low density in 18, circular cystic wall in 11, parenchymatous high density in 4, and mixed density in 6. Long T 1 and T 2 signals with tumor wall nodules were displayed in MRI in all of 12 patients. Postoperative pathology: 47 were cystic tumors with tumor wall nodules in the size of 0 1～3 0cm in diameter. The tumor was solitary in 71 cases, and multiple is 3, and the mixed tumor of glioblastoma multiforme and multiple angioreticuloma was located in the temporal lobe in 1 patient, which was rare. The tumor should be diagnosed as angioreticuloma when it was located in the cerebellar hemisphere or vermis without the feature of midcystic tumor or parenchymatous tumor in CT and MRI profiles, with the features of obvious reinforcement or paramagnetic vascular empty in tumor, and a short history.